Glioblastoma multiforme

Understanding Glioblastoma Multiforme

Glioblastoma multiforme, commonly known as GBM, is a malignant type of brain cancer that originates from the brain’s supportive tissues. It can affect people of all ages but is more prevalent in older adults. GBM is considered one of the most aggressive and dangerous types of brain cancer.

Symptoms and Diagnosis

The symptoms of GBM may vary depending on the location of the tumor, as the tumor can affect different parts of the brain. Some of the common symptoms include severe headache, nausea and vomiting, seizures, difficulty in speaking and understanding, personality and mood changes, and weakness in one side of the body.

The diagnosis of GBM is usually confirmed through imaging tests, such as magnetic resonance imaging (MRI) and computed tomography (CT) scan, and biopsy. A biopsy is a surgical procedure in which a small tissue sample is removed from the brain and examined under a microscope to determine if it is cancerous.

Treatment options

The treatment of GBM usually involves surgery, radiation therapy, and chemotherapy. Depending on the size and location of the tumor, surgery may be performed to remove the tumor as much as possible. Radiation therapy and chemotherapy may be used to destroy the remaining cancer cells.


Despite advances in treatment, the prognosis for GBM is generally poor, with most patients surviving only for a few months to a few years after diagnosis. This is because GBM is highly resistant to treatment, and cancer cells can continue to grow and divide even after treatment.


In conclusion, glioblastoma multiforme is a malignant type of brain cancer that is characterized by its aggressive behavior and poor prognosis. Early detection and treatment are important in improving the chances of survival. However, much more research is needed to better understand this type of cancer and improve treatment options.